Mar 13, 4:00 PM: The Tuesday JFI Seminar - Lutz Maibaum, Department of Chemistry, University of ...
ABSTRACT:Cellular membranes are bilayers made of a large number of different types of phospholipids, sterols, and proteins. Their spatial organization is of fundamental importance for a large number of elementary biological processes including cell signaling and membrane trafficking. It has become clear that phospholipids and sterols contribute significantly to the lateral structure of such membranes. The order that emerges from their interactions spans multiple length scales, which necessitates the use of a wide range of models to study membrane organization with computational methods. In this talk I present our principal discoveries of membrane structure across multiple scales, including new aspects of the condensing effect of cholesterol, the rich phase behavior of multicomponent bilayers, and the effect of membrane fluctuations on protein interactions. For further information please contact Brenda Thomas at 773-702-7156 or by email at bthomas@uchicago.edu. You may also contact the Host, Suri Vaikuntanathan, 773-702-7256 or via email at svaikunt@uchicago.eduDate: March 13, 2018Time: 4:00 PM - 5:00 PM