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Engel Lab Develops Optical Analogue to MRI Using Laser Pulses

By Irene Hsiao

Postdoc Marco Allodi and graduate students John Otto, Ryan Wood, and Richard Mazuski of the Engel group have been developing a technique they call ORI (optical resonance imaging), an optical analog to MRI (magnetic resonance imaging). First proposed in ACS Photonics last November (Optical Resonance Imaging: An Optical Analog to MRI with Subdiffraction-Limited Capabilities), their method uses three quick pulses from a laser for precise imaging. The first two pulses excite the sample; the third, delivered at an angle to the first two, stimulates an optical emission. Measuring the arrival time of this pulse relative to that of a reference pulse allows a spatial and temporal measurement that the group anticipates will permit wide-field superresolution images with femtosecond time resolution.