John Anderson

Research Interests:

The Anderson Lab is a group of synthetic inorganic chemists. While our research is centered upon transition metal chemistry, we find substantial overlap and applicability in a variety of other fields, including organic chemistry, spectroscopy, materials chemistry, and biology. Students in the lab are trained in a variety of synthetic techniques, particularly those related to the isolation and handling of air-sensitive complexes and materials. Furthermore, students gain expertise in the acquisition and interpretation of common analytical methods such as NMR, UV-Vis, and IR spectroscopies, as well as using more advanced data acquired from EPR, XAS, or magnetometry.

At the heart of our research lies the interplay between natural and synthetic systems. We aim to use well-defined synthetic complexes and materials with two main goals. First, we aim to use isolable complexes as models for biological systems, notably as tools to understand some of the fundamental properties that govern enzymatic transformations. Second, we use principles employed by biological systems to develop challenging reactivity or properties in complexes or materials. Other aims include the careful control of spin-state, bi-functional activation of substrates, and the utilization of redox active scaffolds to mediate reactivity and coupling. For more information on these research projects, please visit the Anderson Lab website.

Selected References

“Statistical Analysis of C-H Activation by Transition Metal Oxo Species Supports Thermodynamic Control Over Reactivity” Schneider, J. E.; Goetz, M. K.; Anderson, J. S. Chem. Sci. 2021, 12, 4173-4183.

“Generation and Reactivity of a Ni^III₂(μ-1,2-peroxo) Complex” Zhao, N.; Filatov, A. S.; Xie, J.; Hill, E. A.; Anderson, J. S. J. Am. Chem. Soc. 2020, 142, 21634–21639.

“Reversible Switching of Organic Diradical Character via Iron-Based Spin-Crossover” Kawamura, A.; Xie, J.; Boyn, J-N.; Jesse, K. A.; McNeece, A. J.; Hill, E. A.; Collins, K. A.; Valdez-Moreira, J. A.; Filatov, A. S.; Kurutz, J. W.; Mazziotti, D. A.; Anderson, J. S. J. Am. Chem. Soc. 2020, 142, 17670-17680

“Generation and Oxidative Reactivity of a Ni(II) Superoxo Complex via Ligand-Based Redox Non-Innocence” McNeece, A. J.; Jesse, K. A.; Xie, J.; Filatov, A. S.; Anderson, J. S. J. Am. Chem. Soc. 2020, 142, 10824-10832.

“Redox, Transmetalation, and Stacking Properties of Tetrathiafulvalene-2,3,6,7-tetrathiolate Bridged Tin and Nickel Compounds” Xie, J.; Boyn, J-N.; Filatov, A. S.; McNeece, A. J.; Mazziotti, D. A.; Anderson, J. S. Chem. Sci. 2020, 11, 1066-1078.

“Experimental Evidence for pKa-Driven Asynchronicity in C-H Activation by a Terminal Co(III)-Oxo Complex” Goetz, M. K.; Hill, E. A.; Anderson, J. S. J. Am. Chem. Soc. 2019, 141, 4051-4062.

“Redox-Active 1D Coordination Polymers of Iron-Sulfur Clusters and 1,4-benzendithiol” Horwitz, N. E.; Xie, J.; Filatov, A. S.; Papoular, R. J.; Grahn, M.; Gilder, C.; Anderson, J. S. J. Am. Chem. Soc. 2019, 141, 3940-3951.

"Reversible Homolytic Activation of Water via Metal-Ligand Cooperativity in a T-shaped Ni(II) Complex" Chang, M-C; Jesse, K. A.; Filatov, A. S.; Anderson, J. S. Chem. Sci. 2019, 10, 1360-1367.

"Isolation of a Terminal Co(III)-Oxo Complex" Goetz, M. K.; Hill, E. A.; Filatov, A. S.; Anderson, J. S. J. Am. Chem. Soc., 2018, 140, 13176-13180.

"Isolable Iodosylarene and Iodoxyarene Adducts of Co and Their O-atom Transfer and C-H Activation Reactivity" Hill, E. A.; Kelty, M. L.; Filatov, A. S.; Anderson, J. S. Chem. Sci., 2018, 9, 4493.